The Eqiunox

The Equinox transformation is gained by having 3 Angel room items and 3 Devil deal items or by using 2 The Wise cards in the same run or by using The Wise as True Lilith

Isaac will fire out of both eyes at the same time creating 2 tears, 1 will be white and the other will be black depending on which side. The different colours are cosmetic and dont act differently to normal tears, this is a similar effect to 20/20 but without the damage down